Human RECQL5 Helicase; A Target Enabling Package

Human RECQL5 Helicase; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. RECQL5 is a member of the RecQ family of helicase which have important functions in DNA repair pathways and maintenance of genome integrity. RECQL5 has recently been identified as a synthetic lethal candidate in various...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Gileadi, O
Formatua:	Dataset
Argitaratua:	University of Oxford 2018
Gaiak:	Structural Genomics Chemical Biology Drug Discovery

Antzeko izenburuak

Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Gileadi, O
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
nork: Kopec, J
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
nork: Yue, W
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
Argitaratua: (2018)

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
nork: Dixon-Clarke, S
Argitaratua: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Argitaratua: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
nork: Mathea, S
Argitaratua: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
nork: Bullock, A
Argitaratua: (2018)

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package
Argitaratua: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
nork: Mathea, S
Argitaratua: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
nork: Bullock, A
Argitaratua: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Savitsky, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Savitsky, P
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Carpenter, E
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Chu, A
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Dong, Y
Argitaratua: (2018)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
nork: Newman, J, et al.
Argitaratua: (2017)

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
nork: Bassam Abu-Libdeh, et al.
Argitaratua: (2022-03-01)

Inhibition of KDM4D and stabilisation of the PHF8 plant homeodomain’s transient structural states using antibodies
nork: Wolfreys, F
Argitaratua: (2017)

Application of Fragment-Based Drug Discovery to Versatile Targets
nork: Qingxin Li
Argitaratua: (2020-08-01)

Analysis of multiple compound–protein interactions reveals novel bioactive molecules
nork: Hiroaki Yabuuchi, et al.
Argitaratua: (2011-03-01)

RECQL5 at the Intersection of Replication and Transcription
nork: Zeid Hamadeh, et al.
Argitaratua: (2020-05-01)

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer
nork: Zhu X, et al.
Argitaratua: (2018-12-01)

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.
nork: Wilson Castillo-Tandazo, et al.
Argitaratua: (2019-07-01)

Connecting genetics and gene expression data for target prioritisation and drug repositioning
nork: Enrico Ferrero, et al.
Argitaratua: (2018-05-01)

Targeting the ubiquitin system by fragment-based drug discovery
nork: Cassandra Kennedy, et al.
Argitaratua: (2022-09-01)

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
nork: Maria J. Marcaida, et al.
Argitaratua: (2020-12-01)