Human RECQL5 Helicase; A Target Enabling Package

Human RECQL5 Helicase; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. RECQL5 is a member of the RecQ family of helicase which have important functions in DNA repair pathways and maintenance of genome integrity. RECQL5 has recently been identified as a synthetic lethal candidate in various...

Descrizione completa

Dettagli Bibliografici
Autore principale:	Gileadi, O
Natura:	Dataset
Pubblicazione:	University of Oxford 2018
Soggetti:	Structural Genomics Chemical Biology Drug Discovery

Documenti analoghi

Human RECQL5 Helicase; A Target Enabling Package
di: Newman, J
Pubblicazione: (2018)

Human RECQL5 Helicase; A Target Enabling Package
di: Newman, J
Pubblicazione: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
di: Gileadi, O
Pubblicazione: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Pubblicazione: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
di: Kopec, J
Pubblicazione: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
di: Yue, W
Pubblicazione: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
di: Cox, O
Pubblicazione: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
di: Cox, O
Pubblicazione: (2018)

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
di: Dixon-Clarke, S
Pubblicazione: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Pubblicazione: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
di: Mathea, S
Pubblicazione: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
di: Bullock, A
Pubblicazione: (2018)

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package
Pubblicazione: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
di: Mathea, S
Pubblicazione: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
di: Bullock, A
Pubblicazione: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
di: Pinkas, D
Pubblicazione: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
di: Pinkas, D
Pubblicazione: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
di: Brennan, P
Pubblicazione: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
di: Newman, J
Pubblicazione: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
di: Newman, J
Pubblicazione: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
di: Brennan, P
Pubblicazione: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
di: Brennan, P
Pubblicazione: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
di: Savitsky, P
Pubblicazione: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
di: Brennan, P
Pubblicazione: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
di: Brennan, P
Pubblicazione: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
di: Savitsky, P
Pubblicazione: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
di: Carpenter, E
Pubblicazione: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
di: Chu, A
Pubblicazione: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
di: Dong, Y
Pubblicazione: (2018)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
di: Newman, J, et al.
Pubblicazione: (2017)

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1
di: Bassam Abu-Libdeh, et al.
Pubblicazione: (2022-03-01)

Inhibition of KDM4D and stabilisation of the PHF8 plant homeodomain’s transient structural states using antibodies
di: Wolfreys, F
Pubblicazione: (2017)

Application of Fragment-Based Drug Discovery to Versatile Targets
di: Qingxin Li
Pubblicazione: (2020-08-01)

Analysis of multiple compound–protein interactions reveals novel bioactive molecules
di: Hiroaki Yabuuchi, et al.
Pubblicazione: (2011-03-01)

RECQL5 at the Intersection of Replication and Transcription
di: Zeid Hamadeh, et al.
Pubblicazione: (2020-05-01)

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer
di: Zhu X, et al.
Pubblicazione: (2018-12-01)

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.
di: Wilson Castillo-Tandazo, et al.
Pubblicazione: (2019-07-01)

Connecting genetics and gene expression data for target prioritisation and drug repositioning
di: Enrico Ferrero, et al.
Pubblicazione: (2018-05-01)

Targeting the ubiquitin system by fragment-based drug discovery
di: Cassandra Kennedy, et al.
Pubblicazione: (2022-09-01)

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
di: Maria J. Marcaida, et al.
Pubblicazione: (2020-12-01)