APC in the regulation of intestinal crypt fission.

The functional effects of APC (adenomatous polyposis coli gene) germ-line mutations on crypt fission and cell proliferation were investigated in the normal intestine of human familial adenomatous polyposis (FAP) and multiple intestinal neoplasia (MIN) mice. Compared with controls, there was a 19-fol...

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Hlavní autoři: Wasan, H, Park, H, Liu, K, Mandir, N, Winnett, A, Sasieni, P, Bodmer, W, Goodlad, R, Wright, N
Médium: Journal article
Jazyk:English
Vydáno: 1998