Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.

OBJECTIVE: The incidence of childhood obesity and type 2 diabetes has reached epidemic proportions. Glucocorticoid excess causes central obesity and diabetes mellitus as seen in Cushing's syndrome. The 11beta-hydroxysteroid dehydrogenase type 1 enzyme (11beta-HSD1) regenerates active cortisol...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wiegand, S, Richardt, A, Remer, T, Wudy, SA, Tomlinson, J, Hughes, B, Grüters, A, Stewart, P, Strasburger, C, Quinkler, M
التنسيق: Journal article
اللغة:English
منشور في: 2007