Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.

Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.

OBJECTIVE: The incidence of childhood obesity and type 2 diabetes has reached epidemic proportions. Glucocorticoid excess causes central obesity and diabetes mellitus as seen in Cushing's syndrome. The 11beta-hydroxysteroid dehydrogenase type 1 enzyme (11beta-HSD1) regenerates active cortisol...

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Bibliographic Details
Main Authors:	Wiegand, S, Richardt, A, Remer, T, Wudy, SA, Tomlinson, J, Hughes, B, Grüters, A, Stewart, P, Strasburger, C, Quinkler, M
Format:	Journal article
Language:	English
Published:	2007

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