Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.
OBJECTIVE: The incidence of childhood obesity and type 2 diabetes has reached epidemic proportions. Glucocorticoid excess causes central obesity and diabetes mellitus as seen in Cushing's syndrome. The 11beta-hydroxysteroid dehydrogenase type 1 enzyme (11beta-HSD1) regenerates active cortisol...
| Główni autorzy: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
2007
|