Lobeline for smoking cessation.

BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH STRATEGY: We searched the Cochrane...

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Main Authors: Stead, L, Hughes, JR
Format: Journal article
Language:English
Published: 2000
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author Stead, L
Hughes, JR
author_facet Stead, L
Hughes, JR
author_sort Stead, L
collection OXFORD
description BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register. SELECTION CRITERIA: Randomized trials comparing lobeline to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow-up. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of subjects, the dose and form of lobeline, the outcome measures, method of randomisation, and completeness of follow-up. MAIN RESULTS: We identified no trials meeting the full inclusion criteria including long term follow-up. REVIEWER'S CONCLUSIONS: There is no evidence available from long term trials that lobeline can aid smoking cessation.
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spelling oxford-uuid:30c22757-da7b-46f4-9fc2-3fe431749c7f2022-03-26T13:03:34ZLobeline for smoking cessation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:30c22757-da7b-46f4-9fc2-3fe431749c7fEnglishSymplectic Elements at Oxford2000Stead, LHughes, JR BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register. SELECTION CRITERIA: Randomized trials comparing lobeline to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow-up. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of subjects, the dose and form of lobeline, the outcome measures, method of randomisation, and completeness of follow-up. MAIN RESULTS: We identified no trials meeting the full inclusion criteria including long term follow-up. REVIEWER'S CONCLUSIONS: There is no evidence available from long term trials that lobeline can aid smoking cessation.
spellingShingle Stead, L
Hughes, JR
Lobeline for smoking cessation.
title Lobeline for smoking cessation.
title_full Lobeline for smoking cessation.
title_fullStr Lobeline for smoking cessation.
title_full_unstemmed Lobeline for smoking cessation.
title_short Lobeline for smoking cessation.
title_sort lobeline for smoking cessation
work_keys_str_mv AT steadl lobelineforsmokingcessation
AT hughesjr lobelineforsmokingcessation