Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.

Loss of heterozygosity affecting chromosome 7q is common in acute myeloid leukemia and myelodysplastic syndromes, pointing toward the essential role of this region in disease phenotype and clonal evolution. The higher resolution offered by recently developed genomic platforms may be used to establis...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Jerez, A, Sugimoto, Y, Makishima, H, Verma, A, Jankowska, A, Przychodzen, B, Visconte, V, Tiu, R, O'Keefe, C, Mohamedali, A, Kulasekararaj, A, Pellagatti, A, McGraw, K, Muramatsu, H, Moliterno, A, Sekeres, M, McDevitt, M, Kojima, S, List, A, Boultwood, J, Mufti, G, Maciejewski, J
Format:	Journal article
Sprache:	English
Veröffentlicht:	2012

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.

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