Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit.
Hypoxia-inducible factor-1 (HIF-1), a heterodimeric DNA binding complex composed of two basic-helix-loop-helix Per-AHR-ARNT-Sim proteins (HIF-1alpha and -1beta), is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. To identify re...
Príomhchruthaitheoirí: | Pugh, C, O'Rourke, J, Nagao, M, Gleadle, J, Ratcliffe, P |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
1997
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Míreanna comhchosúla
Míreanna comhchosúla
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