The evolutionary and clinical implications of the uneven distribution of the frequency of the inherited haemoglobin variants over short geographical distances.

Studies of the frequency of heterozygous carriers for common inherited diseases of haemoglobin in over 7500 adolescent children in 25 districts in Sri Lanka have disclosed a highly significant variation over very short geographical distances. A further analysis of these findings, including their rel...

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Main Authors: Premawardhena, A, Allen, A, Piel, F, Fisher, C, Perera, L, Rodrigo, R, Goonathilaka, G, Ramees, L, Peto, T, Olivieri, N, Weatherall, D
Format: Journal article
Jezik:English
Izdano: Wiley 2016