The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

Genetic studies in inflammatory bowel disease have identified multiple susceptibility loci, whose relevance depends critically on verification in independent cohorts. Genetic variants associated with Crohn's disease have now been identified on chromosomes 5 (IBD5/5q31 risk haplotype) and 16 (IB...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	van Heel, D, Dechairo, B, Dawson, G, McGovern, D, Negoro, K, Carey, A, Cardon, L, Mackay, I, Jewell, D, Lench, N
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2003

Παρόμοια τεκμήρια

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.
ανά: Negoro, K, κ.ά.
Έκδοση: (2003)

Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.
ανά: van Heel, D, κ.ά.
Έκδοση: (2002)

Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis.
ανά: McGovern, D, κ.ά.
Έκδοση: (2003)

Strong association between Crohn's disease and a stop codon in tucan (Card8) located within the IBD6 linkage region on chromosome 19
ανά: McGovern, D, κ.ά.
Έκδοση: (2004)

NOD2 (CARD15), the first susceptibility gene for Crohn's disease.
ανά: McGovern, D, κ.ά.
Έκδοση: (2001)

The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease.
ανά: Parkes, M, κ.ά.
Έκδοση: (2000)

Current status of IBD and surgery of Crohn's disease in Thailand
ανά: Woramin Riansuwan, κ.ά.
Έκδοση: (2021-09-01)

Crohn's disease: genetic susceptibility, bacteria, and innate immunity.
ανά: Van Heel, D, κ.ά.
Έκδοση: (2001)

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn’s disease
ανά: Noble, C, κ.ά.
Έκδοση: (2005)

TUCAN (CARD8) genetic variants and inflammatory bowel disease.
ανά: McGovern, D, κ.ά.
Έκδοση: (2006)

The IL23 axis plays a key role in the pathogenesis of IBD.
ανά: McGovern, D, κ.ά.
Έκδοση: (2007)

IBD care in Europe: A comparative audit of the inpatient management of Crohn's disease and ulcerative colitis using the national UK IBD audit tool.
ανά: Cassinotti, A, κ.ά.
Έκδοση: (2009)

The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course
ανά: Jessica Mwinyi, κ.ά.
Έκδοση: (2012-01-01)

Metronidazole overexposure in children and its association with new-onset Crohn’s disease (IBD)
ανά: Mudassir Nisar, κ.ά.
Έκδοση: (2024-01-01)

The contribution of HLA genes to IBD susceptibility and phenotype.
ανά: Yap, L, κ.ά.
Έκδοση: (2004)

Development of an index to define overall disease severity in IBD
ανά: Siegel, C, κ.ά.
Έκδοση: (2016)

Improving the care of inflammatory bowel disease (IBD) patients: perspectives and strategies for IBD center management
ανά: Jihye Park, κ.ά.
Έκδοση: (2021-09-01)

IBD and Diet
ανά: Ilene Gilbert, κ.ά.
Έκδοση: (1994-01-01)

IBD or strongyloidiasis?
ανά: Marta Maia Boscá-Watts, κ.ά.

Microbiota and IBD
ανά: M. Aberg, κ.ά.
Έκδοση: (2020-06-01)

Microbiota and IBD
ανά: B. Wu, κ.ά.
Έκδοση: (2020-01-01)

Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis
ανά: Ivan Giovannini, κ.ά.
Έκδοση: (2024-12-01)

Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity
ανά: Alex Barnes, κ.ά.
Έκδοση: (2024-01-01)

Inflammatory bowel disease (IBD)-disk accurately predicts the daily life burden and parallels disease activity in patients with IBD
ανά: Arshdeep Singh, κ.ά.
Έκδοση: (2023-07-01)

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.
ανά: McGovern, D, κ.ά.
Έκδοση: (2005)

HLA genes are important phenotype determining genes in the peripheral arthropathies of inflammatory bowel disease (IBD).
ανά: Orchard, T, κ.ά.
Έκδοση: (1998)

New IBD Markers: Definition of Disease Heterogeneity
ανά: Stephan R Targan
Έκδοση: (1995-01-01)

Helminth Lessons in Inflammatory Bowel Diseases (IBD)
ανά: Tyler Atagozli, κ.ά.
Έκδοση: (2023-04-01)

Validation of the Portuguese Version of IBD-Control Questionnaire and Comparison with IBD-Disk
ανά: Tânia Carvalho, κ.ά.
Έκδοση: (2024-10-01)

Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®
ανά: Jan de Laffolie, κ.ά.
Έκδοση: (2017-01-01)

Health Literacy of Children and Adolescents with Inflammatory Bowel Disease (IBD) and Parents of IBD Patients—Coping and Information Needs
ανά: Kalina Kaul, κ.ά.
Έκδοση: (2024-04-01)

Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome
ανά: Israr Khan, κ.ά.
Έκδοση: (2019-08-01)

Novel inflammatory bowel disease (IBD) specific electronic medical record allows scalable auditing of IBD severity, therapy and complications to show the current unmet need in IBD care
ανά: Alex Barnes, κ.ά.
Έκδοση: (2022-10-01)

Is IBD different in the elderly?
ανά: Travis, S
Έκδοση: (2008)

IBD: Progress in Pathogenesis
ανά: Claudio Fiocchi, κ.ά.
Έκδοση: (1993-01-01)

IBD considerations in spondyloarthritis
ανά: Caroline Di Jiang, κ.ά.
Έκδοση: (2020-07-01)

IBD and the gut microbiota
ανά: C. Mah, κ.ά.
Έκδοση: (2021-09-01)

Ankylosing spondylitis (AS) in inflammatory bowel disease (IBD) is associated with possession of HLA-B27 and DR1
ανά: Orchard, T, κ.ά.
Έκδοση: (1997)

Geographical heterogeneity in the disease characteristics and management of patients with inflammatory bowel disease, the preliminary results of a Chinese database for IBD (CHASE-IBD)
ανά: Jian Wan, κ.ά.
Έκδοση: (2023-12-01)

Association of IBD specific treatment and prevalence of pain in the Swiss IBD cohort study.
ανά: Lorenz Bon, κ.ά.
Έκδοση: (2019-01-01)