A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

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To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313 high-risk adenoma) and 965 controls. In phase 2, we genotyped 42,708 selected SNPs in 2,873 CRC case...

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Manylion Llyfryddiaeth
Prif Awduron:	Tomlinson, I, Webb, E, Carvajal-Carmona, L, Broderick, P, Howarth, K, Pittman, A, Spain, S, Lubbe, S, Walther, A, Sullivan, K, Jaeger, E, Fielding, S, Rowan, A, Vijayakrishnan, J, Domingo, E, Chandler, I, Kemp, Z, Qureshi, M, Farrington, S, Tenesa, A, Prendergast, J, Barnetson, R, Penegar, S, Barclay, E, Wood, W
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2008

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