Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link.

A variety of different molecular mechanisms have been proposed to explain the suppressive action of regulatory T cells, including the production of anti-inflammatory cytokines, negative costimulatory ligands, indoleamine 2,3-dioxygenase-mediated tryptophan catabolism, CD73-mediated adenosine generat...

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Hlavní autoři: Cobbold, S, Adams, E, Nolan, K, Regateiro, F, Waldmann, H
Médium: Journal article
Jazyk:English
Vydáno: 2010

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