The genome of Salmonella enterica serovar Typhi.
The generation of complete genome sequences provides a blueprint that facilitates the genetic characterization of pathogens and their hosts. The genome of Salmonella enterica serovar Typhi (S. Typhi) harbors ~5 million base pairs encoding some 4000 genes, of which >200 are functionally inacti...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2007
|
| _version_ | 1797061459510820864 |
|---|---|
| author | Baker, S Dougan, G |
| author_facet | Baker, S Dougan, G |
| author_sort | Baker, S |
| collection | OXFORD |
| description | The generation of complete genome sequences provides a blueprint that facilitates the genetic characterization of pathogens and their hosts. The genome of Salmonella enterica serovar Typhi (S. Typhi) harbors ~5 million base pairs encoding some 4000 genes, of which >200 are functionally inactive. Comparison of S. Typhi isolates from around the world indicates that they are highly related (clonal) and that they emerged from a single point of origin ~30,000-50,000 years ago. Evidence suggests that, as well as undergoing gene degradation, S. Typhi has also recently acquired genes, such as those encoding the Vi antigen, by horizontal transfer events. |
| first_indexed | 2024-03-06T20:31:28Z |
| format | Journal article |
| id | oxford-uuid:312f1081-6d9d-48f7-aa02-28861b6ad0b2 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:31:28Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:312f1081-6d9d-48f7-aa02-28861b6ad0b22022-03-26T13:06:19ZThe genome of Salmonella enterica serovar Typhi.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:312f1081-6d9d-48f7-aa02-28861b6ad0b2EnglishSymplectic Elements at Oxford2007Baker, SDougan, GThe generation of complete genome sequences provides a blueprint that facilitates the genetic characterization of pathogens and their hosts. The genome of Salmonella enterica serovar Typhi (S. Typhi) harbors ~5 million base pairs encoding some 4000 genes, of which >200 are functionally inactive. Comparison of S. Typhi isolates from around the world indicates that they are highly related (clonal) and that they emerged from a single point of origin ~30,000-50,000 years ago. Evidence suggests that, as well as undergoing gene degradation, S. Typhi has also recently acquired genes, such as those encoding the Vi antigen, by horizontal transfer events. |
| spellingShingle | Baker, S Dougan, G The genome of Salmonella enterica serovar Typhi. |
| title | The genome of Salmonella enterica serovar Typhi. |
| title_full | The genome of Salmonella enterica serovar Typhi. |
| title_fullStr | The genome of Salmonella enterica serovar Typhi. |
| title_full_unstemmed | The genome of Salmonella enterica serovar Typhi. |
| title_short | The genome of Salmonella enterica serovar Typhi. |
| title_sort | genome of salmonella enterica serovar typhi |
| work_keys_str_mv | AT bakers thegenomeofsalmonellaentericaserovartyphi AT dougang thegenomeofsalmonellaentericaserovartyphi AT bakers genomeofsalmonellaentericaserovartyphi AT dougang genomeofsalmonellaentericaserovartyphi |