"Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.

Symptomatic abnormal periprosthetic soft-tissue reactions ("pseudotumors") have been reported after metal-on-metal hip resurfacing arthroplasty (MoMHRA). The aims of this study were (1) to determine the prevalence of asymptomatic pseudotumors after MoMHRA and (2) to measure metal ion level...

Full description

Bibliographic Details
Main Authors: Kwon, Y, Ostlere, S, McLardy-Smith, P, Athanasou, N, Gill, H, Murray, D
Format: Journal article
Language:English
Published: 2011
_version_ 1797061492647919616
author Kwon, Y
Ostlere, S
McLardy-Smith, P
Athanasou, N
Gill, H
Murray, D
author_facet Kwon, Y
Ostlere, S
McLardy-Smith, P
Athanasou, N
Gill, H
Murray, D
author_sort Kwon, Y
collection OXFORD
description Symptomatic abnormal periprosthetic soft-tissue reactions ("pseudotumors") have been reported after metal-on-metal hip resurfacing arthroplasty (MoMHRA). The aims of this study were (1) to determine the prevalence of asymptomatic pseudotumors after MoMHRA and (2) to measure metal ion levels in these patients. A total of 201 hips in 158 patients were evaluated at a mean follow-up of 61 months (range, 36-88) using ultrasound/magnetic resonance imaging and serum/hip aspirate cobalt and chromium measurements. Pseudotumors found in 7 patients (4%) were associated with significantly higher cobalt and chromium levels and inferior functional scores. Elevated levels of cobalt and chromium ions suggest that pseudotumors are associated with increased wear generated from metal-on-metal articulations. Clinicians need to be aware of pseudotumors as a differential diagnosis during clinical evaluation of MoMHRA patients, and further imaging such as ultrasound or magnetic resonance imaging is recommended to confirm the diagnosis.
first_indexed 2024-03-06T20:31:57Z
format Journal article
id oxford-uuid:31586a99-12d0-4210-86e0-ba3b43b26ff1
institution University of Oxford
language English
last_indexed 2024-03-06T20:31:57Z
publishDate 2011
record_format dspace
spelling oxford-uuid:31586a99-12d0-4210-86e0-ba3b43b26ff12022-03-26T13:07:22Z"Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:31586a99-12d0-4210-86e0-ba3b43b26ff1EnglishSymplectic Elements at Oxford2011Kwon, YOstlere, SMcLardy-Smith, PAthanasou, NGill, HMurray, DSymptomatic abnormal periprosthetic soft-tissue reactions ("pseudotumors") have been reported after metal-on-metal hip resurfacing arthroplasty (MoMHRA). The aims of this study were (1) to determine the prevalence of asymptomatic pseudotumors after MoMHRA and (2) to measure metal ion levels in these patients. A total of 201 hips in 158 patients were evaluated at a mean follow-up of 61 months (range, 36-88) using ultrasound/magnetic resonance imaging and serum/hip aspirate cobalt and chromium measurements. Pseudotumors found in 7 patients (4%) were associated with significantly higher cobalt and chromium levels and inferior functional scores. Elevated levels of cobalt and chromium ions suggest that pseudotumors are associated with increased wear generated from metal-on-metal articulations. Clinicians need to be aware of pseudotumors as a differential diagnosis during clinical evaluation of MoMHRA patients, and further imaging such as ultrasound or magnetic resonance imaging is recommended to confirm the diagnosis.
spellingShingle Kwon, Y
Ostlere, S
McLardy-Smith, P
Athanasou, N
Gill, H
Murray, D
"Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title "Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title_full "Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title_fullStr "Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title_full_unstemmed "Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title_short "Asymptomatic" pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study.
title_sort asymptomatic pseudotumors after metal on metal hip resurfacing arthroplasty prevalence and metal ion study
work_keys_str_mv AT kwony asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy
AT ostleres asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy
AT mclardysmithp asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy
AT athanasoun asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy
AT gillh asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy
AT murrayd asymptomaticpseudotumorsaftermetalonmetalhipresurfacingarthroplastyprevalenceandmetalionstudy