Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity.

Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity.

HIV-1 attenuation resulting from immune escape mutations selected in Gag may contribute to slower disease progression in HIV-1-infected individuals expressing certain HLA class I alleles. We previously showed that the protective allele HLA-B*81 and the HLA-B*81-selected Gag T186S mutation are strong...

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Bibliographic Details
Main Authors:	Wright, J, Naidoo, V, Brumme, Z, Prince, J, Claiborne, D, Goulder, P, Brockman, M, Hunter, E, Ndung'u, T
Format:	Journal article
Language:	English
Published:	2012

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