Structural changes in glycogen phosphorylase induced by phosphorylation.
A comparison of the refined crystal structures of dimeric glycogen phosphorylase b and a reveals structural changes that represent the first step in the activation of the enzyme. On phosphorylation of serine-14, the N-terminus of each subunit assumes an ordered helical conformation and binds to the...
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Bibliographic Details
Main Authors: |
Sprang, SR,
Acharya, K,
Goldsmith, E,
Stuart, D,
Varvill, K,
Fletterick, R,
Madsen, N,
Johnson, L |
Format: | Journal article
|
Language: | English |
Published: |
1988
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