Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.

The minimal signalling unit for tyrosine kinase receptors is two protomers dimerized by one or more ligands. However, it is clear that maximal signalling requires the formation of larger complexes of many receptors at discrete foci on the cell surface. The biological interactions that lead to this a...

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Dettagli Bibliografici
Autori principali:	Harmer, N, Robinson, C, Adam, L, Ilag, L, Gallagher, J, Blundell, T
Natura:	Journal article
Lingua:	English
Pubblicazione:	2006

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