Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
The minimal signalling unit for tyrosine kinase receptors is two protomers dimerized by one or more ligands. However, it is clear that maximal signalling requires the formation of larger complexes of many receptors at discrete foci on the cell surface. The biological interactions that lead to this a...
Những tác giả chính: | Harmer, N, Robinson, C, Adam, L, Ilag, L, Gallagher, J, Blundell, T |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2006
|
Những quyển sách tương tự
-
Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex.
Bằng: Harmer, N, et al.
Được phát hành: (2004) -
Myocardial protection by heparin-based coacervate of FGF10
Bằng: Zhouguang Wang, et al.
Được phát hành: (2021-07-01) -
Crosstalk between Fibroblast Growth Factor (FGF) Receptor and Integrin through Direct Integrin Binding to FGF and Resulting Integrin-FGF-FGFR Ternary Complex Formation
Bằng: Seiji Mori, et al.
Được phát hành: (2013-08-01) -
Comparison of FGF-8, FGF-10, FGF-Receptor 2, Androgen Receptor, Estrogen Receptor-A and SS in Healthy and Hypospadiac Children
Bằng: Emaratpardaz N, et al.
Được phát hành: (2024-09-01) -
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
Bằng: Mateusz Adam Krzyscik, et al.
Được phát hành: (2017-07-01)