Silencing of Dok-7 in adult rat muscle increases susceptibility to passive transfer myasthenia gravis
Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies that target proteins at the neuromuscular junction, primarily the acetylcholine receptor (AChR) and the muscle-specific kinase. Because downstream of kinase 7 (Dok-7) is essential for the full activation of muscle-specific ki...
主要な著者: | , , , , , , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Elsevier
2016
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