Silencing of Dok-7 in adult rat muscle increases susceptibility to passive transfer myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies that target proteins at the neuromuscular junction, primarily the acetylcholine receptor (AChR) and the muscle-specific kinase. Because downstream of kinase 7 (Dok-7) is essential for the full activation of muscle-specific ki...

Полное описание

Библиографические подробности
Главные авторы: Gomez, A, Stevens, J, Mané-Damas, M, Molenaar, P, Duimel, H, Verheyen, F, Cossins, J, Beeson, D, De Baets, M, Losen, M, Martinez-Martinez, P
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2016