Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia.

Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia.

We have investigated the neuroprotective effects of combining an NMDA or AMPA receptor antagonist with a nitric oxide synthase (NOS) inhibitor in the gerbil model of global cerebral ischaemia. Ischaemia was induced by occlusion of the common carotid arteries for 5 min. (5R,10S)-(+)-5-methyl-10,11-di...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Hicks, C, Ward, M, Swettenham, J, O'Neill, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1999

Eitemau Tebyg

NMDA antagonists: their role in neuroprotection.
gan: Small, D, et al.
Cyhoeddwyd: (1997)

NMDA antagonists: their role in neuroprotection.
gan: Small, D, et al.
Cyhoeddwyd: (1997)

Effect of neuronal nitric oxide synthase inhibitors and antioxidants in an experimental model of Parkinson's disease in the rat
gan: Hicks, C, et al.
Cyhoeddwyd: (2000)

Cerebral blood flow alteration in neuroprotection following cerebral ischaemia.
gan: Sutherland, B, et al.
Cyhoeddwyd: (2011)

Cerebral blood flow alteration in neuroprotection following cerebral ischaemia
gan: Sutherland, B, et al.
Cyhoeddwyd: (2011)

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
gan: Xue, D, et al.
Cyhoeddwyd: (1994)

Inhalation gases or gaseous mediators as neuroprotectants for cerebral ischaemia.
gan: Sutherland, B, et al.
Cyhoeddwyd: (2013)

DELAYED TREATMENT WITH AMPA BUT NOT NMDA GLUTAMATE ANTAGONISTS REDUCES NEOCORTICAL INFARCTION
gan: Xue, D, et al.
Cyhoeddwyd: (1992)

AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
gan: Buchan, A, et al.
Cyhoeddwyd: (1993)

POSTISCHEMIC TREATMENT WITH AMPA, BUT NOT NMDA, ANTAGONISTS PREVENTS CA1 NEURONAL INJURY
gan: Li, H, et al.
Cyhoeddwyd: (1992)

NEUROPROTECTIVE PROFILE OF FPL-15896AR, A NOVEL UNCOMPETITIVE NMDA ANTAGONIST
gan: Murray, R, et al.
Cyhoeddwyd: (1995)

CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.
gan: Menniti, F, et al.
Cyhoeddwyd: (2003)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.
gan: Chen, R, et al.
Cyhoeddwyd: (2014)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
gan: Chen, R, et al.
Cyhoeddwyd: (2014)

Neuroprotective effects of nicotine in two experimental models of Parkinson's disease in the rat
gan: Murray, T, et al.
Cyhoeddwyd: (2000)

Do NMDA antagonists protect against cerebral ischemia: are clinical trials warranted?
gan: Buchan, A
Cyhoeddwyd: (1990)

Inducible nitric oxide synthase polymorphism and fatal cerebral malaria.
gan: Burgner, D, et al.
Cyhoeddwyd: (1998)

Do NMDA antagonists prevent neuronal injury? No.
gan: Buchan, A
Cyhoeddwyd: (1992)

The rise and fall of NMDA antagonists for ischemic stroke.
gan: Hoyte, L, et al.
Cyhoeddwyd: (2004)

Antiplatelet therapy in acute cerebral ischaemia.
gan: Sandercock, P, et al.
Cyhoeddwyd: (1999)

PSYCHOPHARMACOLOGICAL PROFILE OF THE NMDA RECEPTOR ANTAGONIST MK-801
gan: Iversen, S, et al.
Cyhoeddwyd: (1987)

The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke.
gan: Buchan, A, et al.
Cyhoeddwyd: (1992)

Brain swelling and ischaemia in Kenyans with cerebral malaria.
gan: Newton, C, et al.
Cyhoeddwyd: (1994)

The effects of cerebral ischaemia on pericytes and neurovascular function
gan: Neuhaus, A
Cyhoeddwyd: (2016)

Mathematical modelling of cerebral ischaemia-reperfusion injury
gan: Mokhtarudin, M
Cyhoeddwyd: (2016)

Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malaria.
gan: Maneerat, Y, et al.
Cyhoeddwyd: (2000)

Neuroprotective effects of omega-Aga-IVA against in vitro ischaemia in the rat hippocampal slice.
gan: Small, D, et al.
Cyhoeddwyd: (1995)

Short-term prognosis following acute cerebral ischaemia
gan: Kennedy, J, et al.
Cyhoeddwyd: (2002)

NMDA receptor antagonists can enhance or impair learning performance in animals.
gan: Mondadori, C, et al.
Cyhoeddwyd: (1989)

Development of early predictors of cerebral ischaemia after subarachnoid haemorrhage
gan: Garry, P
Cyhoeddwyd: (2015)

Neuroprotective potentials of honey for cerebral small vessel disease
gan: Che Mohd Nassir, Che Mohd Nasril, et al.
Cyhoeddwyd: (2022)

Systemic NMDA receptor antagonist CGP-40116 does not impair memory acquisition but protects against NMDA neurotoxicity in rhesus monkeys.
gan: Gutnikov, SA, et al.
Cyhoeddwyd: (1996)

Teaching and research in Malaysian public universities: Synergistic or antagonistic?
gan: Norzaini Azman, et al.
Cyhoeddwyd: (2014)

Tetrahydrobiopterin and nitric oxide synthase recouplers
gan: Channon, KM
Cyhoeddwyd: (2020)

Nitric oxide synthases in heart failure.
gan: Carnicer, R, et al.
Cyhoeddwyd: (2013)

Delayed cerebral ischaemia after subarachnoid haemorrhage: looking beyond vasospasm.
gan: Rowland, M, et al.
Cyhoeddwyd: (2012)

Large artery disease in patients with cerebral ischaemia: frequency, investigation and management
gan: Marquardt, L, et al.
Cyhoeddwyd: (2010)

NMDA-receptor antagonists disrupt the formation of the auditory space map in the mammalian superior colliculus.
gan: Schnupp, J, et al.
Cyhoeddwyd: (1995)

Endothelial nitric oxide synthase and heart rate.
gan: Herring, N, et al.
Cyhoeddwyd: (2002)

Histological features of carotid plaque in patients with ocular ischaemia versus cerebral events
gan: Howard, D, et al.
Cyhoeddwyd: (2013)