Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia.

Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia.

We have investigated the neuroprotective effects of combining an NMDA or AMPA receptor antagonist with a nitric oxide synthase (NOS) inhibitor in the gerbil model of global cerebral ischaemia. Ischaemia was induced by occlusion of the common carotid arteries for 5 min. (5R,10S)-(+)-5-methyl-10,11-di...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Hicks, C, Ward, M, Swettenham, J, O'Neill, M
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1999

Παρόμοια τεκμήρια

Effect of neuronal nitric oxide synthase inhibitors and antioxidants in an experimental model of Parkinson's disease in the rat
ανά: Hicks, C, κ.ά.
Έκδοση: (2000)

Narrow temporal therapeutic window for NMDA antagonist protection against focal cerebral ischaemia
ανά: Gary K. Steinberg, κ.ά.
Έκδοση: (1995-04-01)

NMDA antagonists: their role in neuroprotection.
ανά: Small, D, κ.ά.
Έκδοση: (1997)

NMDA antagonists: their role in neuroprotection.
ανά: Small, D, κ.ά.
Έκδοση: (1997)

Neuroprotection, excitotoxicicity and nmda antagonists
ανά: RUBENS JOSÉ GAGLIARDI
Έκδοση: (2000-06-01)

Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
ανά: Xue, D, κ.ά.
Έκδοση: (1994)

DELAYED TREATMENT WITH AMPA BUT NOT NMDA GLUTAMATE ANTAGONISTS REDUCES NEOCORTICAL INFARCTION
ανά: Xue, D, κ.ά.
Έκδοση: (1992)

Cerebral blood flow alteration in neuroprotection following cerebral ischaemia.
ανά: Sutherland, B, κ.ά.
Έκδοση: (2011)

Cerebral blood flow alteration in neuroprotection following cerebral ischaemia
ανά: Sutherland, B, κ.ά.
Έκδοση: (2011)

AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
ανά: Buchan, A, κ.ά.
Έκδοση: (1993)

POSTISCHEMIC TREATMENT WITH AMPA, BUT NOT NMDA, ANTAGONISTS PREVENTS CA1 NEURONAL INJURY
ανά: Li, H, κ.ά.
Έκδοση: (1992)

Inhalation gases or gaseous mediators as neuroprotectants for cerebral ischaemia.
ανά: Sutherland, B, κ.ά.
Έκδοση: (2013)

Neuroprotective effects of nicotine in two experimental models of Parkinson's disease in the rat
ανά: Murray, T, κ.ά.
Έκδοση: (2000)

CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.
ανά: Menniti, F, κ.ά.
Έκδοση: (2003)

NEUROPROTECTIVE PROFILE OF FPL-15896AR, A NOVEL UNCOMPETITIVE NMDA ANTAGONIST
ανά: Murray, R, κ.ά.
Έκδοση: (1995)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.
ανά: Chen, R, κ.ά.
Έκδοση: (2014)

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
ανά: Chen, R, κ.ά.
Έκδοση: (2014)

Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies
ανά: Gniewomir Latacz, κ.ά.
Έκδοση: (2022-01-01)

Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain
ανά: Stephen M. Black, κ.ά.
Έκδοση: (1995-06-01)

Aerobic exercise repairs neurological function after cerebral ischaemia by regulating the nitric oxide
ανά: LEI SUN, κ.ά.

Evaluation of the neuroprotective and antioxidant effects of Dorema aucheri extract on cerebral ischaemia-reperfusion injury in rats
ανά: Javad Rasouli Vani, κ.ά.
Έκδοση: (2019-01-01)

Acute Footshock Stress Induces Time-Dependent Modifications of AMPA/NMDA Protein Expression and AMPA Phosphorylation
ανά: Daniela Bonini, κ.ά.
Έκδοση: (2016-01-01)

Prenatal hypoxia-induced adaptation and neuroprotection that is inducible nitric oxide synthase-dependent
ανά: Ping Zhao, κ.ά.
Έκδοση: (2005-12-01)

Do NMDA antagonists protect against cerebral ischemia: are clinical trials warranted?
ανά: Buchan, A
Έκδοση: (1990)

Inducible nitric oxide synthase polymorphism and fatal cerebral malaria.
ανά: Burgner, D, κ.ά.
Έκδοση: (1998)

Differential expression of AMPA subunits induced by NMDA intrahippocampal injection in rats
ανά: Helene Aparecida Fachim, κ.ά.
Έκδοση: (2016-02-01)

NMDA and Ampa receptors in synaptic membranes of cocaine and cocaine-prazosin treated rats
ανά: W. I. Silva, κ.ά.
Έκδοση: (2005-03-01)

Therapeutic potential of AMPA receptor antagonist perampanel against cerebral ischemia: beyond epileptic disorder
ανά: Satoshi Suda, κ.ά.
Έκδοση: (2019-01-01)

Expression of AMPA and NMDA receptor subunits in the cervical spinal cord of wobbler mice
ανά: Corsi Massimiliano M, κ.ά.
Έκδοση: (2006-10-01)

Antiplatelet therapy in acute cerebral ischaemia.
ανά: Sandercock, P, κ.ά.
Έκδοση: (1999)

NMDA Receptor Antagonists for Treatment of Depression
ανά: Zeynep Ates-Alagoz, κ.ά.
Έκδοση: (2013-04-01)

Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs
ανά: Sanderson Thomas M, κ.ά.
Έκδοση: (2011-07-01)

NMDA and AMPA Receptors at Synapses: Novel Targets for Tau and α-Synuclein Proteinopathies
ανά: Maria Italia, κ.ά.
Έκδοση: (2022-06-01)

Differential modulation of NMDA and AMPA receptors by cellular prion protein and copper ions
ανά: Sun Huang, κ.ά.
Έκδοση: (2018-10-01)

Synergy of AMPA and NMDA receptor currents in dopaminergic neurons: a modeling study
ανά: Denis eZakharov, κ.ά.
Έκδοση: (2016-05-01)

Ionotropic Glutamate Receptors in Epilepsy: A Review Focusing on AMPA and NMDA Receptors
ανά: Takahisa Hanada
Έκδοση: (2020-03-01)

Mathematical modelling of cerebral ischaemia-reperfusion injury
ανά: Mokhtarudin, M
Έκδοση: (2016)

Natural reward experience alters AMPA and NMDA receptor distribution and function in the nucleus accumbens.
ανά: Kyle K Pitchers, κ.ά.
Έκδοση: (2012-01-01)

Neuroprotective Effect of Smilacis chinae Rhizome on NMDA-Induced Neurotoxicity In Vitro and Focal Cerebral Ischemia In Vivo
ανά: Ju Yeon Ban, κ.ά.
Έκδοση: (2008-01-01)

Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malaria.
ανά: Maneerat, Y, κ.ά.
Έκδοση: (2000)