Influence of pH on the conformation and stability of mismatch base-pairs in DNA.

A series of self-complementary dodecanucleotide duplexes containing two symmetrically disposed mismatches have been studied by pH-dependent, ultraviolet light melting techniques. The results indicate that A.C, and C.C mismatches are strongly stabilized by protonation and that the degree of stabiliza...

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Hlavní autoři: Brown, T, Leonard, G, Booth, E, Kneale, G
Médium: Journal article
Jazyk:English
Vydáno: 1990