Influence of pH on the conformation and stability of mismatch base-pairs in DNA.
A series of self-complementary dodecanucleotide duplexes containing two symmetrically disposed mismatches have been studied by pH-dependent, ultraviolet light melting techniques. The results indicate that A.C, and C.C mismatches are strongly stabilized by protonation and that the degree of stabiliza...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
1990
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