Hypertrophic cardiomyopathy due to sarcomeric gene mutations is characterized by impaired energy metabolism irrespective of the degree of hypertrophy.

OBJECTIVES: We investigated cardiac energetics in subjects with mutations in three different familial hypertrophic cardiomyopathy (HCM) disease genes, some of whom were nonpenetrant carriers without hypertrophy, using phosphorus-31 magnetic resonance spectroscopy. BACKGROUND: Familial hypertrophic c...

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書目詳細資料
Main Authors: Crilley, J, Boehm, E, Blair, E, Rajagopalan, B, Blamire, A, Styles, P, McKenna, W, Ostman-Smith, I, Clarke, K, Watkins, H
格式: Journal article
語言:English
出版: 2003