Synthesis and pairing properties of oligonucleotides containing 3-hydroxy-4-hydroxymethyl-1-cyclohexanyl nucleosides
The enantiomeric forms of cyclohexanyl adenine and thymine nucleosides were obtained by separation of their diastereomeric esters with (R)-(-)-methylmandelic acid. The four nucleoside analogues were appropriately protected, converted to their phosphoramidites and oligomerized. The resulting cyclohex...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
1999
|