Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care
As currently designed and conducted, randomized controlled trials rarely address the complexity of patient characteristics that need to be taken into account when making clinical decisions in primary care. We introduce the concept of a response adaptive, platform trial design, as this approach may...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Royal College of General Practitioners
2018
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_version_ | 1826266129555783680 |
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author | Butler, C Connor, J Lewis, R Broglio, K Saville, B Cook, J van der Velden, A Verheij, T |
author_facet | Butler, C Connor, J Lewis, R Broglio, K Saville, B Cook, J van der Velden, A Verheij, T |
author_sort | Butler, C |
collection | OXFORD |
description | As currently designed and conducted, randomized controlled trials rarely address the complexity of patient characteristics that need to be taken into account when making clinical decisions in primary care. We introduce the concept of a response adaptive, platform trial design, as this approach may be better suited to answering patient-centred, primary care research questions. |
first_indexed | 2024-03-06T20:34:15Z |
format | Journal article |
id | oxford-uuid:321698de-f92a-4972-b323-ed5c87db606a |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T20:34:15Z |
publishDate | 2018 |
publisher | Royal College of General Practitioners |
record_format | dspace |
spelling | oxford-uuid:321698de-f92a-4972-b323-ed5c87db606a2022-03-26T13:11:52ZAnswering patient-centred questions efficiently: Response-adaptive platform trials in primary careJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:321698de-f92a-4972-b323-ed5c87db606aEnglishSymplectic Elements at OxfordRoyal College of General Practitioners2018Butler, CConnor, JLewis, RBroglio, KSaville, BCook, Jvan der Velden, AVerheij, TAs currently designed and conducted, randomized controlled trials rarely address the complexity of patient characteristics that need to be taken into account when making clinical decisions in primary care. We introduce the concept of a response adaptive, platform trial design, as this approach may be better suited to answering patient-centred, primary care research questions. |
spellingShingle | Butler, C Connor, J Lewis, R Broglio, K Saville, B Cook, J van der Velden, A Verheij, T Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title | Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title_full | Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title_fullStr | Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title_full_unstemmed | Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title_short | Answering patient-centred questions efficiently: Response-adaptive platform trials in primary care |
title_sort | answering patient centred questions efficiently response adaptive platform trials in primary care |
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