Mouse models of human chromosomal translocations and approaches to cancer therapy.

Mouse models of human chromosomal translocations and approaches to cancer therapy.

Cancer arises because of genetic changes in somatic cells, eventually giving rise to overt malignancy. Principle among genetic changes found in tumor cells are chromosomal translocations which give rise to fusion genes or enforced oncogene expression. These mutations are tumor-specific and result in...

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Autors principals:	Rabbitts, T, Appert, A, Chung, G, Collins, E, Drynan, L, Forster, A, Lobato, M, McCormack, M, Pannell, R, Spandidos, A, Stocks, MR, Tanaka, T, Tse, E
Format:	Journal article
Idioma:	English
Publicat:	2001

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