Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCB...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Cambridge University Press
2019
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| _version_ | 1826266146698952704 |
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| author | Harrison, PJ Tunbridge, EM Dolphin, AC Hall, J |
| author_facet | Harrison, PJ Tunbridge, EM Dolphin, AC Hall, J |
| author_sort | Harrison, PJ |
| collection | OXFORD |
| description | We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications. |
| first_indexed | 2024-03-06T20:34:30Z |
| format | Journal article |
| id | oxford-uuid:322ab1f7-a94c-4629-9741-211d0d9d0822 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:34:30Z |
| publishDate | 2019 |
| publisher | Cambridge University Press |
| record_format | dspace |
| spelling | oxford-uuid:322ab1f7-a94c-4629-9741-211d0d9d08222022-03-26T13:12:25ZVoltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisalJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:322ab1f7-a94c-4629-9741-211d0d9d0822EnglishSymplectic Elements at OxfordCambridge University Press2019Harrison, PJTunbridge, EMDolphin, ACHall, JWe reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications. |
| spellingShingle | Harrison, PJ Tunbridge, EM Dolphin, AC Hall, J Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title | Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title_full | Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title_fullStr | Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title_full_unstemmed | Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title_short | Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal |
| title_sort | voltage gated calcium channel blockers for psychiatric disorders genomic reappraisal |
| work_keys_str_mv | AT harrisonpj voltagegatedcalciumchannelblockersforpsychiatricdisordersgenomicreappraisal AT tunbridgeem voltagegatedcalciumchannelblockersforpsychiatricdisordersgenomicreappraisal AT dolphinac voltagegatedcalciumchannelblockersforpsychiatricdisordersgenomicreappraisal AT hallj voltagegatedcalciumchannelblockersforpsychiatricdisordersgenomicreappraisal |