Ets, Ap-1 and GATA factor families regulate the utrophin B promoter: potential regulatory mechanisms for endothelial-specific expression.
Duchenne muscular dystrophy is caused by dystrophin deficiency, which can be prevented in the mdx mouse model by over-expression of an autosomal homologue, utrophin. Utrophin has two characterised full-length promoters, A and B. No data are available on the transcriptional regulation of B utrophin,...
Main Authors: | Perkins, K, Davies, K |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2003
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פריטים דומים
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Understanding the endothelial function of utrophin.
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Regulation of utrophin in transgenic mice.
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The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
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Novel 5 '-utrophin isoforms exhibit species-specific transcriptional profiles and provide additional candidates for therapeutic up-regulation in DMD
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The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
מאת: Perkins, K, et al.
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