The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer

The definitive characterization of common cancer stem cell (CSCs) subpopulations in breast cancer subtypes with distinct genotypic and phenotypic features remains an ongoing challenge. In this study, we have used a non-biased genome wide screening approach to identify transcriptional networks that m...

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Những tác giả chính: Walsh, CA, Akrap, N, Garre, E, Magnusson, Y, Harrison, H, Andersson, D, Jonasson, E, Rafnsdottir, S, Choudhry, H, Buffa, F, Ragoussis, J, Ståhlberg, A, Harris, A, Landberg, G
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Public Library of Science 2020

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