The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer

The definitive characterization of common cancer stem cell (CSCs) subpopulations in breast cancer subtypes with distinct genotypic and phenotypic features remains an ongoing challenge. In this study, we have used a non-biased genome wide screening approach to identify transcriptional networks that m...

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Bibliografiske detaljer
Main Authors: Walsh, CA, Akrap, N, Garre, E, Magnusson, Y, Harrison, H, Andersson, D, Jonasson, E, Rafnsdottir, S, Choudhry, H, Buffa, F, Ragoussis, J, Ståhlberg, A, Harris, A, Landberg, G
Format: Journal article
Sprog:English
Udgivet: Public Library of Science 2020