Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function that defines CKD, in 312,468 individuals of d...

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Main Authors: Morris, A, Le, T, Wu, H, Akbarov, A, Van Der Most, P, Hemani, G, Smith, G, Mahajan, A, Gaulton, K, Nadkarni, G, Valladares-Salgado, A, Wacher-Rodarte, N, Mychaleckyj, J, Dueker, N, Guo, X, Hai, Y, Haessler, J, Kamatani, Y, Stilp, A, Zhu, G, Cook, J, Ärnlöv, J, Blanton, S, De Borst, M, Bottinger, E, Buchanan, T, Cechova, S, Charchar, F, Chu, P, Damman, J, Eales, J, Gharavi, A, Giedraitis, V, Heath, A, Ipp, E, Kiryluk, K, Kramer, H, Kubo, M, Larsson, A, Lindgren, C, Lu, Y, Madden, P, Montgomery, G, Papanicolaou, G, Raffel, L, Sacco, R, Sanchez, E, Stark, H, Sundstrom, J, Taylor, K, Xiang, A, Zivkovic, A, Lind, L, Ingelsson, E, Martin, N, Whitfield, J, Cai, J, Laurie, C, Okada, Y, Matsuda, K, Kooperberg, C, Chen, Y, Rundek, T, Rich, S, Loos, R, Parra, E, Cruz, M, Rotter, J, Snieder, H, Tomaszewski, M, Humphreys, B, Franceschini, N
格式: Journal article
语言:English
出版: Springer Nature 2019

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