Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.

HLA-B*57 is the class I allele most consistently associated with control of human immunodeficiency virus (HIV) replication, which may be linked to the specific HIV peptides that this allele presents to cytotoxic T lymphocytes (CTLs), and the resulting efficacy of these cellular immune responses. In...

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Bibliographic Details
Main Authors: Crawford, H, Lumm, W, Leslie, A, Schaefer, M, Boeras, D, Prado, J, Tang, J, Farmer, P, Ndung'u, T, Lakhi, S, Gilmour, J, Goepfert, P, Walker, B, Kaslow, R, Mulenga, J, Allen, S, Goulder, P, Hunter, E
Format: Journal article
Language:English
Published: 2009