Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs.

Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs.

The anthracyclines, such as doxorubicin (DXR), are potent anti-cancer drugs but they are limited by their clinical toxicity. The mechanisms involved remain poorly understood partly because of the difficulty in determining sub-cellular drug localisation. Using a novel method utilising the fluorescent...

書目詳細資料
Main Authors:	Ashley, N, Poulton, J
格式:	Journal article
語言:	English
出版:	2009

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