Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs.

The anthracyclines, such as doxorubicin (DXR), are potent anti-cancer drugs but they are limited by their clinical toxicity. The mechanisms involved remain poorly understood partly because of the difficulty in determining sub-cellular drug localisation. Using a novel method utilising the fluorescent...

Повний опис

Бібліографічні деталі
Автори: Ashley, N, Poulton, J
Формат: Journal article
Мова:English
Опубліковано: 2009