Fluid-mechanics Simulations of Ventricular Function under LVAD Support

LVAD implantation is often used to assist patients suffering heart failure. These devices profoundly alter ventricular behaviour, however, the precise impact on the myocardium and on ventricular blood flow remains unknown. We have developed an anatomically accurate coupled fluid-mechanical model of...

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Bibliographic Details
Main Authors: McCormick, M, Nordsletten, D, de Vecchi, A, Kay, D, Smith, P
Format: Journal article
Language:English
Published: 2010
Description
Summary:LVAD implantation is often used to assist patients suffering heart failure. These devices profoundly alter ventricular behaviour, however, the precise impact on the myocardium and on ventricular blood flow remains unknown. We have developed an anatomically accurate coupled fluid-mechanical model of the left ventricle under LVAD support to enhance understanding of the fluid structure interactions that occur during LVAD function. This can be used to optimise LVAD function through minimising blood recirculation and maximising the efficient transduction of cellular work by the ventricle during the cardiac cycle.