Entropic organization of interphase chromosomes
Chromosomes are not distributed randomly in nuclei. Appropriate positioning can activate (or repress) genes by bringing them closer to active (or inactive) compartments like euchromatin (or heterochromatin), and this is usually assumed to be driven by specific local forces (e.g., involving H bonds b...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Rockefeller University Press
2009
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