The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.
We summarize the genetic and clinical features of the colorectal adenomas and cancers that occur in MYH-associated polyposis (MAP). MAP results from biallelic germline mutations in the base excision repair gene, mutY homologue (MYH). MAP has a phenotype that is often indistinguishable from classical...
Päätekijät: | Lipton, L, Tomlinson, I |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2004
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