The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.

The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.

We summarize the genetic and clinical features of the colorectal adenomas and cancers that occur in MYH-associated polyposis (MAP). MAP results from biallelic germline mutations in the base excision repair gene, mutY homologue (MYH). MAP has a phenotype that is often indistinguishable from classical...

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Autori principali:	Lipton, L, Tomlinson, I
Natura:	Journal article
Lingua:	English
Pubblicazione:	2004

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