The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.

We summarize the genetic and clinical features of the colorectal adenomas and cancers that occur in MYH-associated polyposis (MAP). MAP results from biallelic germline mutations in the base excision repair gene, mutY homologue (MYH). MAP has a phenotype that is often indistinguishable from classical...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lipton, L, Tomlinson, I
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2004