Characterization of an evolutionarily conserved far-upstream enhancer in the human alpha 2(I) collagen (COL1A2) gene.

We have examined the chromatin structure around and upstream of the transcriptional start site of the human alpha2(I) collagen (COL1A2) gene. Four strong DNase I-hypersensitive sites (HS2-5) were only detected in fibroblasts, and a weaker one (HS1) was identified in type I collagen-negative cells. A...

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Bibliographic Details
Main Authors: Antoniv, T, De Val, S, Wells, D, Denton, C, Rabe, C, de Crombrugghe, B, Ramirez, F, Bou-Gharios, G
Format: Journal article
Language:English
Published: 2001