A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys.

A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys.

Antigenic diversity has posed a critical barrier to vaccine development against the pathogenic blood-stage infection of the human malaria parasite Plasmodium falciparum. To date, only strain-specific protection has been reported by trials of such vaccines in nonhuman primates. We recently showed tha...

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書誌詳細
主要な著者: Douglas, A, Baldeviano, G, Lucas, C, Lugo-Roman, L, Crosnier, C, Bartholdson, S, Diouf, A, Miura, K, Lambert, L, Ventocilla, J, Leiva, K, Milne, K, Illingworth, J, Spencer, A, Hjerrild, K, Alanine, D, Turner, A, Moorhead, J, Edgel, K, Wu, Y, Long, C, Wright, G, Lescano, A, Draper, S
フォーマット: Journal article
言語:English
出版事項: Cell Press 2015

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