Tuning the formation of a covalent haem-protein link by selection of reductive or oxidative conditions as exemplified by ascorbate peroxidase.
Previous work [Metcalfe, Ott, Patel, Singh, Mistry, Goff and Raven (2004) J. Am. Chem. Soc. 126, 16242-16248] has shown that the introduction of a methionine residue (S160M variant) close to the 2-vinyl group of the haem in ascorbate peroxidase leads to the formation of a covalent haem-methionine li...
Үндсэн зохиолчид: | Metcalfe, C, Daltrop, O, Ferguson, S, Raven, E |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2007
|
Ижил төстэй зүйлс
Ижил төстэй зүйлс
-
Autocatalytic formation of a covalent link between tryptophan 41 and the heme in ascorbate peroxidase.
-н: Pipirou, Z, зэрэг
Хэвлэсэн: (2007) -
Autocatalytic formation of green heme: evidence for H2O2-dependent formation of a covalent methionine-heme linkage in ascorbate peroxidase.
-н: Metcalfe, C, зэрэг
Хэвлэсэн: (2004) -
Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase.
-н: Pipirou, Z, зэрэг
Хэвлэсэн: (2009) -
Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase.
-н: Murphy, E, зэрэг
Хэвлэсэн: (2008) -
Nitric Oxide Inhibition of Tobacco Catalase and Ascorbate Peroxidase
-н: Daniel Clark, зэрэг
Хэвлэсэн: (2000-12-01)