Therapeutic manipulation of the HIF hydroxylases.

The hypoxia-inducible factor (HIF) family of transcription factors is responsible for coordinating the cellular response to low oxygen levels in animals. By regulating the expression of a large array of target genes during hypoxia, these proteins also direct adaptive changes in the hematopoietic, ca...

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Main Authors: Nagel, S, Talbot, N, Mecinović, J, Smith, T, Buchan, A, Schofield, C
格式: Journal article
语言:English
出版: 2010