Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.

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The synthesis and inhibitory potencies of a novel series of 3,5-diaryl-1H-pyrazoles as specific inhibitors of prokaryotic arylamine N-acetyltransferase enzymes is described. The series is based on hit compound 1 3,5-diaryl-1H-pyrazole identified from a high-throughout screen that has been carried ou...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Fullam, E, Talbot, J, Abuhammed, A, Westwood, I, Davies, S, Russell, A, Sim, E
פורמט:	Journal article
שפה:	English
יצא לאור:	2013

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