Global role for polyadenylation-assisted nuclear RNA degradation in posttranscriptional gene silencing.

Global role for polyadenylation-assisted nuclear RNA degradation in posttranscriptional gene silencing.

Fission yeast Cid14, a component of the TRAMP (Cid14/Trf4-Air1-Mtr4 polyadenylation) complex, polyadenylates nuclear RNA and stimulates degradation by the exosome for RNA quality control. Here, we analyze patterns of global gene expression in cells lacking the Cid14 or the Dis3/Rpr44 subunit of the...

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Bibliographic Details
Main Authors:	Wang, S, Stevenson, A, Kearsey, S, Watt, S, Bähler, J
Format:	Journal article
Language:	English
Published:	2008

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