Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study

Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study

<p><strong>Objective:</strong> Levels of chitotriosidase (CHIT1) are increased in the cerebrospinal fluid (CSF) of amyotrophic lateral sclerosis (ALS) patients reflecting microglial activation. Here, we determine the diagnostic and prognostic potential of CHIT1 for early symptomati...

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Main Authors: Steinacker, P, Feneberg, E, Halbgebauer, S, Witzel, S, Verde, F, Oeckl, P, Van Damme, P, Gaur, N, Gray, E, Grosskreutz, J, Jardel, CG, Kachanov, M, Kuhle, J, Lamari, F, Maceski, A, del Mar Amador, M, Mayer, B, Morelli, C, Petri, S, Poesen, K, Raaphorst, J, Salachas, F, Silani, V, Turner, M, Verbeek, MM, Volk, AE, Weishaupt, JH, Weydt, P, Ludolph, AC, Otto, M
Format: Journal article
Language:English
Published: Taylor and Francis 2021

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