Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay.

Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay.

Macrophages (Mphi) may play an important role in the pathogenesis of invasive meningococcal infection. Previously, we have shown that the class A Mphi scavenger receptor (SR-A) is a major nonopsonic receptor for Neisseria meningitidis on Mphi. SR-A contributes to host defense by binding proinflammat...

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Bibliographic Details
Main Authors:	Peiser, L, Makepeace, K, Plüddemann, A, Savino, S, Wright, J, Pizza, M, Rappuoli, R, Moxon, E, Gordon, S
Format:	Journal article
Language:	English
Published:	2006

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